PhysiologyThe FASEB JournalPeer-reviewed
Knock out of the intracellular calcium conducting ion channel Mitsugumin 23 (MG23) protects against pressure overload induced left ventricular hypertrophy and cardiac dysfunction.
Amy M Dorward, Gavin B. Robertson, Claire C. Sneddon…·Samantha Jane Pitt
This study shows that knocking out MG23 protects against pressure overload-induced cardiac hypertrophy and dysfunction by reducing Ca2+ leak from the sarcoplasmic reticulum.
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