PRDM16 Coordinates Genetic and Epigenetic Programs Governing Chondrogenesis and Chondrocyte Phenotype Specification in the Knee Joint
Eloise Fadial, Victoria L. Hansen, Gulzada Kulzhanova, Eliya Tazreena Tashbib, Deeksha Chinta, Alexis Klee, Helen Shammas, Gourango Pradhan, Chia‐Lung Wu
This study identifies PRDM16 as a critical regulator of chondrogenesis and chondrocyte identity in the knee joint through DNA binding and histone modification.
bioRxiv · Jan 31, 2026 · PreprintPathology