Author

Guanrui Liao

Beth Israel Deaconess Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:spatial transcriptomics· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:clustering· 2 Research Focus:dimensionality reduction· 2 Organism:human· 2 Research Focus:cell-cell communication· 1 Assay:CITE-seq· 1

Frequent Co-Authors

Bokai ZhuiD· 3 shared Garry P. NolaniD· 3 shared Sizun JiangiD· 3 shared Alex K. ShalekiD· 2 shared Amy Y. HuangiD· 2 shared Han M. CheniD· 2 shared Jason YeungiD· 2 shared Scott J. RodigiD· 2 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersBioinformatics

Bokai ZhuORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Epstein-Barr Virus Orchestrates Spatial Reorganization and Immunomodulation within the Classic Hodgkin Lymphoma Tumor Microenvironment

Yao Yu Yeo, Huaying Qiu, Yunhao Bai, Bokai Zhu, Yuzhou Chang, Fabio Iannelli, Stephanie Pei Tung Yiu, Jason Yeung, Hendrik A. Michel, Yuchen Wang, Yang Wang, Wenrui Wu, K. T. Wright, Muhammad Shaban, Sam Sadigh, , Sizun Jiang

This study uses spatial multi-omics to compare EBV-positive and EBV-negative cHL, identifying distinct TME features and immunological signatures linked to EBV.

Cell Reports Medicine · Mar 31, 2026Peer-reviewedCancer Biology

Cross-domain information fusion for enhanced cell population delineation in single-cell spatial-omics data

Bokai Zhu, Sheng Gao, Shuxiao Chen, Jason Yeung, Yunhao Bai, Amy Y. Huang, Yao Yu Yeo, Guanrui Liao, Shulin Mao, Sizun Jiang, Scott J. Rodig, Alex K. Shalek, Garry P. Nolan, Zongming Ma

This paper introduces CellSNAP, a self-supervised method that integrates spatial, transcriptomic, and proteomic data to improve cell population delineation in spatial-omics datasets.

bioRxiv · May 12, 2024 · PreprintBioinformatics

Robust Single-cell Matching and Multi-modalAnalysis Using Shared and Distinct FeaturesReveals Orchestrated Immune Responses

Bokai Zhu, Shuxiao Chen, Yunhao Bai, Han M. Chen, Guanrui Liao, Nilanjan Mukherjee, Gustavo Vazquez, David R. McIlwain, Alexandar Tzankov, Ivan T. Lee, Matthias Sebastian Matter, Yury Goltsev, Zongming Ma, Garry P. Nolan, Sizun Jiang

The paper introduces MARIO, a cell matching algorithm that integrates single-cell proteomic and multi-modal data, revealing orchestrated immune responses in lung tissue.

Nature Methods · Jan 9, 2023Peer-reviewedBioinformatics