Infection-experienced HSPCs protect against infections by generating neutrophils with enhanced bactericidal activity
H. Darroch, P. Keerthisinghe, Y. J. Sung, A. Prankerd-Gough, P. Crosier, J. Astin, C. Hall
The paper shows infection-experienced HSPCs generate neutrophils with enhanced bactericidal activity, contributing to trained immunity and suggesting therapeutic strategies for infectious diseases.
bioRxiv · Nov 3, 2022 · PreprintImmunology