Author

H. Hackl

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Approach:benchmark study· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

H. F. Alkan· 2 shared J. Bogner-Strauss· 2 shared M. Vander Heiden· 2 shared A. Villunger· 1 shared C. Soratroi· 1 shared G. Hoefler· 1 shared G. Karbon· 1 shared H. Fiegl· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

H. F. Alkan

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The BH3-only protein NOXA serves as an independent predictor of breast cancer patient survival and defines susceptibility to microtubule targeting agents

G. Karbon, M. D. Haschka, H. Hackl, C. Soratroi, L. Rocamora-Reverte, W. Parson, H. Fiegl, A. Villunger

This study identifies NOXA as an independent prognostic marker for breast cancer survival and shows its role in predicting response to microtubule-targeting agents.

bioRxiv · May 26, 2021Cancer Biology

Loss of malate-aspartate shuttle component SLC25A12 induces pulmonary metastasis

H. F. Alkan, P. Vesely, H. Hackl, J. Fosselteder, M. Vander Heiden, M. Pichler, G. Hoefler, J. Bogner-Strauss

This study shows that loss of SLC25A12 reduces cytosolic aspartate and impairs tumor growth and metastasis in vivo, but not in vitro.

bioRxiv · May 29, 2020Cancer Biology

N-acetylaspartate improves cell survival when glucose is limiting

H. F. Alkan, K. E. Walter, H. Hackl, M. Vander Heiden, T. Madl, J. Bogner-Strauss

The paper shows N-acetylaspartate (NAA) supports cell survival in low-glucose conditions by maintaining UDP-GlcNAc levels and reducing ER stress, independent of its breakdown into aspartate or acetate.

bioRxiv · May 28, 2020 · PreprintCancer Biology