Author

A. Villunger

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Organism:human· 2 Research Focus:protein structure prediction· 2

Frequent Co-Authors

D. C. J. Spierings· 2 shared F. Foijer· 2 shared G. Karbon· 2 shared A. de Bruin· 1 shared A. Tijhuis· 1 shared B. Westendorp· 1 shared C. Soratroi· 1 shared F. Schuler· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersCell Biology

D. C. J. Spierings

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Chronic deregulation of the spindle assembly checkpoint triggers myelosuppression and gastrointestinal atrophy

A. Villunger, G. Karbon, F. Schuler, M. Haschka, M. Drach, R. Sotillo, S. Geley, D. C. J. Spierings, A. Tijhuis, F. Foijer

The paper investigates the effects of chronic SAC activation in mice, finding it causes bone marrow aplasia and intestinal atrophy, with BIM playing a critical role in gastrointestinal cell death.

bioRxiv · Sep 8, 2023 · PreprintCell Biology

The miR-15a/16-1 and miR-15b/16-2 clusters regulate early B cell development by limiting IL-7 receptor expression

K. Hutter, S. Herzog, A. Villunger, T. Rülicke, L. Andersen, T. Szabo

This study shows that miR-15a/16-1 and miR-15b/16-2 clusters regulate early B cell development by limiting IL-7 receptor expression, leading to increased pro-B cell proliferation.

bioRxiv · Mar 18, 2022Immunology

The BH3-only protein NOXA serves as an independent predictor of breast cancer patient survival and defines susceptibility to microtubule targeting agents

G. Karbon, M. D. Haschka, H. Hackl, C. Soratroi, L. Rocamora-Reverte, W. Parson, H. Fiegl, A. Villunger

This study identifies NOXA as an independent prognostic marker for breast cancer survival and shows its role in predicting response to microtubule-targeting agents.

bioRxiv · May 26, 2021Cancer Biology

PIDDosome-induced p53-activation for ploidy restriction facilitates hepatocarcinogenesis

V. C. Sladky, K. Knapp, T. G. Szabo, L. Bongiovanni, H. van den Bos, D. C. J. Spierings, B. Westendorp, T. Stojakovic, H. Scharnagl, G. Timelthaler, K. Tsuchia, M. Pinter, F. Foijer, A. de Bruin, T. Reiberger, , A. Villunger

This study shows that PIDDosome-mediated ploidy restriction prevents hepatocellular carcinoma by reducing tumor burden and that low ploidy predicts poor survival in HCC patients.

bioRxiv · May 13, 2020 · PreprintCancer Biology