Author

H. Koehler

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 3 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Approach:statistical model· 1

Frequent Co-Authors

A. G. Goodman· 1 shared C. A. Osbron· 1 shared C. J. Carlson· 1 shared C. Lawson· 1 shared D. J. Becker· 1 shared D. Kalman· 1 shared E. S. Mocarski· 1 shared F. Cingolani· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperMicrobiology

A. G. Goodman

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3 papers

Recent·Most cited

Caspase-8 activity mediates TNFα production and restricts Coxiella burnetii replication during murine macrophage infection

C. A. Osbron, C. Lawson, N. Hanna, H. Koehler, A. G. Goodman

This study investigates how caspase-8 regulates TNFα production and restricts Coxiella burnetii replication in macrophages during infection.

bioRxiv · Feb 2, 2024 · PreprintMicrobiology

Viral genomic features predict orthopoxvirus reservoir hosts

K. K. Tseng, H. Koehler, D. J. Becker, R. Gibb, C. J. Carlson, M. d. P. Fernandez, S. N. Seifert

The paper uses machine learning to predict orthopoxvirus reservoir hosts by integrating viral genomic features and host ecological data, identifying high-risk regions for zoonotic OPV emergence.

bioRxiv · Oct 26, 2023 · PreprintMicrobiology

The host-directed therapeutic imatinib mesylate accelerates immune responses to Mycobacterium marinum infection and limits pathology associated with granulomas

T. Cleverley, S. Peddineni, J. Guarner, F. Cingolani, H. Koehler, E. S. Mocarski, D. Kalman

This study shows imatinib accelerates immune responses to Mycobacterium marinum infection and reduces granuloma-associated pathology.

bioRxiv · Nov 28, 2022Immunology