Alpha kinase 3 signaling at the M-band maintains sarcomere integrity and proteostasis in striated muscle.
J. W. McNamara, B. L. Parker, H. K. Voges, N. R. R. Mehdiabadi, F. Bolk, D. D. Chung, N. Charitakis, J. Molendijk, S. Lal, M. Ramialison, K. Karavendzas, H. L. Pointer, P. Syrris, L. R. Lopes, E. M. Perry, , D. A. Elliott
This study identifies ALPK3's role in maintaining sarcomere integrity and proteostasis in striated muscle by localizing to the M-band and interacting with SQSTM1.
bioRxiv · Sep 1, 2022Cell Biology