Structure and Neutralization Mechanism of a Human Antibody Targeting a Complex Epitope on Zika Virus
C. Adams, D. L. Carbaugh, B. Sho, T.-S. Ng, I. Castillo, R. Bhowmik, B. Segovia-Chumbez, A. C. P. Ana C. Puhl, S. Graham, s. diehl, H. Lazear, A. M. de Silva, S.-m. Lok, L. Premkumar
This study defines the epitope and neutralization mechanism of a human antibody targeting Zika virus by showing that cross-linking of viral envelope proteins is critical for neutralization.
bioRxiv · Aug 22, 2022Microbiology