Author

H. Melhem

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Assay:metagenomics· 1 Assay:proteomics· 1

Frequent Co-Authors

B. Kaya· 2 shared P. Wuggenig· 2 shared T. Kaymak· 2 shared C. Cavelti-Weder· 1 shared C. Donas Cuadra· 1 shared C. Riedel· 1 shared E. Flint· 1 shared E. J. Villablanca· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

B. Kaya

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Epithelial GPR35 protects from Citrobacter rodentium infection by preserving goblet cells and mucosal barrier integrity

H. Melhem, B. Kaya, T. Kaymak, P. Wuggenig, E. Flint, J. Roux, C. Cavelti-Weder, M. Balmer, J.-C. Walser, R. Morales, C. Riedel, P. Liberali, E. Villablanca, J. Niess

This study shows that epithelial Gpr35 maintains goblet cell function and mucosal barrier integrity, protecting against Citrobacter rodentium infection.

bioRxiv · Mar 27, 2021Immunology

Lysophosphatidic acid-mediated GPR35 signaling in CX3CR1+ macrophages regulates the intestinal cytokine milieu

B. Kaya, C. Donas Cuadra, P. Wuggenig, O. E. Diaz, R. A. Morales, H. Melhem, Swiss IBD Cohort Investigators, P. P. Hernandez, T. Kaymak, S. Das, P. Hruz, K. Ayata, E. J. Villablanca, J. H. Niess

This study shows that GPR35 signaling in CX3CR1+ macrophages, mediated by lysophosphatidic acid, regulates intestinal cytokine production and inflammation.

bioRxiv · Feb 3, 2020Immunology