H. Neiswender

This study identifies BicD cargo interactome and shows that Egl is required for BicD to link cargos to Dynein, with a SMA mutation affecting cargo transport and mobility.

The paper identifies Egalitarian's interactome using proximity biotin ligation in Drosophila egg chambers, revealing novel partners and a nanobody-based strategy for interactome mapping.

This study shows that Dlc-mediated dimerization of Egl is essential for mRNA binding and oocyte fate in Drosophila, but artificial dimerization only partially rescues these functions.

The paper identifies the role of Dlc in promoting Egl dimerization, which is essential for RNA binding and subsequent association with the Dynein motor for mRNA localization.