BioengineeringbioRxiv
Combating viral contaminants in CHO cells by engineering STAT1 mediated innate immunity
A. W. T. Chiang, S. Li, B. P. Kellman…·N. E. Lewis
The paper identifies Gfi1 and Trim24 as repressors of STAT1 in CHO cells and shows that knocking them out increases resistance to RNA viruses.
DOI 10.1038/s41598-019-45126-x