Human Surfactant Protein D Binds S1 and Receptor Binding Domain of Spike protein and acts as an entry inhibitor of SARS-CoV-2 Pseudotyped viral particles in vitro
M.-H. Hsieh, N. Beirag, V. Murugaiah, Y.-C. Chou, W.-S. Kuo, H.-F. Kao, T. Madan, U. Kishore, J.-Y. Wang
This study shows that rfhSP-D binds SARS-CoV-2 S1 protein and inhibits viral entry into cells, suggesting its potential as an antiviral therapy.
bioRxiv · Dec 18, 2020Microbiology