Pentose Phosphate Pathway Inhibition activates Macrophages towards phagocytic Lymphoma Cell Clearance
A. C. Beielstein, E. Izquierdo, S. J. Blakemore, N. Nickel, M. Michalik, S. Chawan, R. Brinker, H.-H. Bartel, D. Vorholt, J. L. Nolte, R. Linke, C. R. Costa Picosi, J. Saiz, F. Picard, J. Meinel, , C. P. Pallasch
This study shows that inhibiting the pentose phosphate pathway enhances macrophage phagocytosis of lymphoma cells and improves survival in a mouse model.
bioRxiv · Jun 9, 2023 · PreprintCancer Biology