Pan-cancer scale screening reveals NRF2 associated immunoevasive characteristics in non-small cell lung cancer and squamous malignancies
J. Harkonen, P. Polonen, A. Jawahar-Deen, I. Selvarajan, H.-R. Teppo, E. Dimova, T. Kietzmann, M. Ahtiainen, T. Eklund, T. Kuopio, E.-M. Talvitie, P. Taimen, M. Kallajoki, M. U. Kaikkonen, M. Heinaniemi, A.-L. Levonen
This paper identifies NRF2-associated immunoevasive features in NSCLC and squamous cancers, linking NRF2 activity to immune-cold phenotypes and potential biomarkers for immune checkpoint response.
bioRxiv · May 15, 2022 · PreprintCancer Biology