P. Polonen

Sequential drug treatment targeting cell cycle and cell fate regulatory programs blocks non-genetic cancer evolution in acute lymphoblastic leukemia

Integrative Analysis of Histological Textures and Lymphocyte Infiltration in Renal Cell Carcinoma using Deep Learning

This study uses deep learning to analyze histological textures and lymphocyte infiltration in renal cell carcinoma, finding associations between tissue features and clinical outcomes.

Pan-cancer scale screening reveals NRF2 associated immunoevasive characteristics in non-small cell lung cancer and squamous malignancies

This paper identifies NRF2-associated immunoevasive features in NSCLC and squamous cancers, linking NRF2 activity to immune-cold phenotypes and potential biomarkers for immune checkpoint response.

Signaling input from divergent pathways subverts malignant B-cell transformation

This study shows that malignant B-cell transformation requires convergence on a single oncogenic pathway, while divergent pathways can subvert transformation and are targets for new therapeutic strategies.

Immunogenomic landscape of hematological malignancies

This study links immunological features to cancer subtypes, genetic alterations, and patient survival in hematological malignancies using integrated genomic and transcriptomic data.