PTEN inhibition promotes robust growth of bulbospinal respiratory axons and partial recovery of diaphragm function in a chronic model of cervical contusion spinal cord injury
Pauline Michel‐Flutot, Lan Cheng, Samantha J. Thomas, Brianna Lisi, Harrison Schwartz, Sandy Lam, Megan A. Lyttle, David A. Jaffe, George M. Smith, Shuxin Li, Megan C. Wright, Angelo C. Lepore
This study shows that PTEN inhibition promotes partial diaphragm function recovery and axon growth in chronic cervical spinal cord injury, while PTPσ inhibition does not.
bioRxiv · Jan 10, 2024Neuroscience