Galvanin (TMEM154) is an electric-field sensor for directed cell migration
Nathan M. Belliveau, Matthew J. Footer, Amy Platenkamp, Celeste Rodriguez, Heonsu Kim, Christopher K. Prinz, Aaron Paul van Loon, Yubin Lin, Tara E. Eustis, Michelle M. Chan, Daniel J. Cohen, Julie A. Theriot
A CRISPRi migration screen in neutrophil-like HL-60 cells identified Galvanin (TMEM154), a single-pass membrane protein whose negatively charged ectodomain electrophoreses anodally to steer cathodal electrotaxis.
Cell · May 12, 2026Peer-reviewedCell Biology✦ In-depth digest