Author

Honghong Sun

University of Pennsylvania

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Andrea Preising· 1 shared Armando RodrígueziD· 1 shared Chiara PastorioiD· 1 shared Drew WeissmaniD· 1 shared Emmanouil PapasavvasiD· 1 shared Frank KirchhoffiD· 1 shared Gregory M. LairdiD· 1 shared Houping NiiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

Andrea Preising

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2 papers

Recent·Most cited

Anionic lipids modulate mRNA-lipid nanoparticle immunogenicity and confer protection in a mouse model of multiple sclerosis

Jilian R. Melamed, Jenna Muscat-Rivera, Michael Kegel, Lesley S. Chaboub, Roxanne Perez‐Tremble, Navdeep S. Bhalla, Houping Ni, Honghong Sun, Drew Weissman

This study shows that anionic lipids in mRNA-LNPs can modulate immune responses, reducing inflammation and disease in a multiple sclerosis mouse model.

bioRxiv · Oct 17, 2025 · PreprintBioengineering

Retinol Binding Protein 4 reactivates latent HIV-1 via the JAK/STAT5 and JNK pathways

Chiara Pastorio, Khumoekae Richard, Manuel Hayn, Lennart Koepke, Andrea Preising, Nico Preising, Ludger Ständker, Matthew G. Fair, Jessicamarie Morris, Emmanouil Papasavvas, Honghong Sun, Armando Rodríguez, Karam Mounzer, Sebastian Wiese, Pablo Tebas, , Frank Kirchhoff

This study identifies Retinol Binding Protein 4 (RBP4) as a natural activator of latent HIV-1 through JAK/STAT5 and JNK pathways, offering a new strategy for reactivating viral reservoirs.

bioRxiv · Feb 26, 2025 · PreprintImmunology