CIRKO: A chemical-induced reversible gene knockout system for studying gene function in situ
Hui Shi, Qin Jin, Fangbing Chen, Zhen Ouyang, Shixue Gou, Xiaoyi Liu, Lei Li, Shuangshuang Mu, Chengdan Lai, Quanjun Zhang, Yinghua Ye, Kepin Wang, Liangxue Lai
The paper introduces a chemical-induced reversible gene knockout system (CIRKO) that allows for controlled inactivation and reactivation of genes in primary cells and animal models.
bioRxiv · Aug 31, 2022 · PreprintGenetics