Author

Hui Wu

Oregon Health & Science University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Bioinformatics· 2 Neuroscience· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:perturbation response prediction· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Organism:bacteria (other)· 1

Frequent Co-Authors

Xian ZhangiD· 2 shared Abigail N. RobertsoniD· 1 shared Ayisha ZiaiD· 1 shared Caitlyn C. SebastianiD· 1 shared Chen FengiD· 1 shared Chenhao Zhou· 1 shared Chin-Teng Lin· 1 shared DanDan Yan· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersBioinformatics

Xian ZhangORCID

Author profile →

5 papers

Recent·Most cited

The archaic CUP pilus SMF-1 uses an antiparallel bundling mechanism to initiate biofilm formation

Jessie Lynda Fields, Caitlyn C. Sebastian, Hua Zhang, Radhika Bhaumik, Ayisha Zia, Abigail N. Robertson, Gregory G. Anderson, Seema Mattoo, Hui Wu, Megan R. Kiedrowski, Fengbin Wang

This study reveals the structure and bundling mechanism of SMF-1, a CUP pilus in Stenotrophomonas maltophilia, showing it forms antiparallel bundles that initiate biofilm formation.

Cell Reports · Oct 1, 2026Peer-reviewedMicrobiology

DELPHAI predicts heterogeneous perturbation responses with learned single-cell fitness

Xian Zhang, Hui Wu, Haikun Liu

DELPHAI predicts heterogeneous perturbation responses by jointly training a fitness network and optimal transport network to identify differentially expressed genes and depleted cell lineages.

bioRxiv · Sep 17, 2026 · PreprintBioinformatics

DELPHAI, AI Agent for Predicting Drug Response and Resistance

Tianping Peng, Hui Wu, Hai‐Kun Liu, Xian Zhang

DELPHAI predicts drug response and resistance using single-cell perturbation data from organoids, identifying mechanisms and recommending therapies.

bioRxiv · Sep 12, 2025 · PreprintBioinformatics

Acoustic inspired brain-to-sentence decoder for logosyllabic language

Chen Feng, Lu Cao, Di Wu, En Zhang, Ting Wang, Xiaowei Jiang, Chenhao Zhou, Jinbo Chen, Hui Wu, Siyu Lin, Qiming Hou, Chin-Teng Lin, 朱君明, Jie Yang, Mohamad Sawan, Yue Zhang

This paper develops a brain-to-sentence decoder for Mandarin Chinese, achieving 71% character accuracy by leveraging acoustic features and language models.

Cyborg and Bionic Systems · Jan 1, 2025Peer-reviewedNeuroscience

Restoring the loss of consciousness under sevoflurane anesthesia in states of anxiety and depression by potently activating serotonergic pathways in brain

Yuling Wang, Yue Yang, YaXuan Wu, Xiaoxia Xu, WeiHui Shao, Shuai Li, Qing Xu, LeYuan Gu, Lu Liu, ZiWen Zhang, XuanYi Di, Hui Wu, DanDan Yan, Yue Shen, XinZhong Chen, Honghai Zhang

This study identifies a serotonergic pathway between the central amygdala and medial prefrontal cortex that accelerates sevoflurane anesthesia recovery, particularly in individuals with anxiety and depression.

bioRxiv · Jun 19, 2024 · PreprintNeuroscience