Restoring the loss of consciousness under sevoflurane anesthesia in states of anxiety and depression by potently activating serotonergic pathways in brain
Yuling Wang, Yue Yang, YaXuan Wu, Xiaoxia Xu, WeiHui Shao, Shuai Li, Qing Xu, LeYuan Gu, Lu Liu, ZiWen Zhang, XuanYi Di, Hui Wu, DanDan Yan, Yue Shen, XinZhong Chen, Honghai Zhang
This study identifies a serotonergic pathway between the central amygdala and medial prefrontal cortex that accelerates sevoflurane anesthesia recovery, particularly in individuals with anxiety and depression.
bioRxiv · Jun 19, 2024 · PreprintNeuroscience