ERK basal and pulsatile activity are differentially regulated in mammalian epidermis to control proliferation and exit from the stem cell compartment
T. Hiratsuka, I. Bordeu, G. Pruessner, F. M. Watt
The paper shows that ERK activity in mammalian epidermis is regulated by pulsatile and basal dynamics, with DUSP10 and DUSP6 controlling different aspects of differentiation.
bioRxiv · Apr 12, 2020Cell Biology