Protein Structure Inspired Drug Discovery
F. Qiao, A. Binkowski, I. Broughan, W. Chen, A. Natarajan, G. Schiltz, K. Scheidt, W. Anderson, R. Bergan
The paper uses protein 3D structure analysis to discover novel anticancer compounds by targeting unique structural motifs, identifying Dxr2-017 as a selective inhibitor of melanoma cells.
bioRxiv · May 17, 2024 · PreprintCancer Biology