A genomic duplication spanning multiple P450s contributes to insecticide resistance in the dengue mosquito Aedes aegypti
T. Bacot, C. Haberkorn, J. Guilliet, J. Cattel, M. Kefi, L. Nadalin, J. Filee, F. Boyer, T. Gaude, F. Laporte, J. Tutagata, J. Vontas, I. Dusfour, J.-M. Bonneville, J.-P. David
This study identifies a genomic duplication of multiple P450 genes in Aedes aegypti that enhances deltamethrin resistance and reveals its evolutionary origin and fitness costs.
bioRxiv · Apr 3, 2024Evolutionary Biology