F. Boyer

A genomic duplication spanning multiple P450s contributes to insecticide resistance in the dengue mosquito Aedes aegypti

This study identifies a genomic duplication of multiple P450 genes in Aedes aegypti that enhances deltamethrin resistance and reveals its evolutionary origin and fitness costs.

Multiple adaptive solutions to face climatic constraints: novel insights in the debate over the role of convergence in local adaptation

The paper compares adaptive trajectories in sheep and goats to explore genomic convergence in local adaptation, finding few shared adaptive genes and suggesting diverse mechanisms.

Splice switching oligonucleotide mediated gene knockdown in B cells and plasma cells

This paper demonstrates the effectiveness of splice switching oligonucleotides in knocking down c-REL and RELA expression in B cells and plasma cells, with potential therapeutic applications in B-lineage cancers.

Glomerulosclerosis and kidney failure in a mouse model of monoclonal immunoglobulin light-chain deposition disease

This study develops a mouse model of light chain deposition disease, showing that pathogenic light chains cause glomerulosclerosis and kidney failure, and identifies potential therapeutic targets.

Reproducing Transformation of Indolent B-cell Lymphoma by T-cell Immunosuppression of L.CD40 Mice.

The paper shows that T-cell immunosuppression in L.CD40 mice transforms indolent B-cell lymphoma into an aggressive form, highlighting immune surveillance's role in disease progression.

Soil community assembly varies across body sizes in a tropical forest

The paper shows that soil community assembly varies with body size, with microorganisms influenced by environmental factors and mesofauna showing random distribution in a tropical forest.