Mice Humanized for Major Histocompatibility Complex and Angiotensin-Converting Enzyme 2 with High Permissiveness to SARS-CoV-2 Omicron Replication
F. Le Chevalier, P. Authie, S. Chardenoux, M. Bourgine, B. Vesin, D. Cussigh, Y. Sassier, I. Fert, A. Noirat, K. Nemirov, F. ANNA, M. BERARD, F. Guinet, D. Hardy, P. Charneau, , L. MAJLESSI
This paper develops hACE2 transgenic mice with high permissiveness to SARS-CoV-2 Omicron replication and uses them to test a vaccine candidate.
bioRxiv · Dec 1, 2022 · PreprintMicrobiology