Author

I. McMullen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:statistical model· 2 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

M. K. Jolly· 3 shared A. R. Subbalakshmi· 2 shared J. Somarelli· 2 shared S. Sahoo· 2 shared A. J. Armstrong· 1 shared A. N. Saxena· 1 shared E. Chen· 1 shared J. A. Somarelli· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersCancer Biology

M. K. Jolly

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3 papers

Recent·Most cited

The ELF3 transcription factor is associated with an epithelial phenotype and represses epithelial-mesenchymal transition

A. R. Subbalakshmi, S. Sahoo, P. Manjunatha, S. Goyal, V. A. Kasiviswanathan, Y. M, S. R, I. McMullen, J. Somarelli, M. K. Jolly

The paper identifies ELF3 as an epithelial-associated transcription factor that inhibits EMT and stabilizes hybrid E/M phenotypes, with potential prognostic implications in solid tumors.

bioRxiv · Aug 19, 2022Cancer Biology

KLF4 induces Mesenchymal-Epithelial Transition (MET) by suppressing multiple EMT-inducing transcription factors

A. R. Subbalakshmi, S. Sahoo, I. McMullen, A. N. Saxena, S. K. Venugopal, J. Somarelli, M. K. Jolly

This study shows KLF4 suppresses EMT-inducing transcription factors and promotes MET, acting as a potential MET-TF with implications for cancer survival.

Cancers · Oct 13, 2021Peer-reviewedCancer Biology

Analysis of immune subtypes across the epithelial-mesenchymal plasticity spectrum

P. Chakraborty, E. Chen, I. McMullen, A. J. Armstrong, M. K. Jolly, J. A. Somarelli

The paper analyzes immune subtypes across the epithelial-mesenchymal plasticity spectrum in cancers, finding heterogeneity in EMT status and associations between immune subtypes and EMT scores.

bioRxiv · Mar 22, 2021Cancer Biology