Author

I. Merelli

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1

Frequent Co-Authors

A. A. Chetta· 1 shared A. Assanelli· 1 shared A. Conti· 1 shared A. Kajaste-Rudnitski· 1 shared A. Laurenzi· 1 shared A. M. S. Giordano· 1 shared A. Matarese· 1 shared A. Santoro· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperImmunology

A. A. Chetta

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Therapy-induced senescence upregulates antigen presentation machinery and triggers anti-tumor immunity in Acute Myeloid Leukemia

D. Gilioli, S. Fusco, T. Tavella, K. Giannetti, A. Conti, A. Santoro, E. Carsana, S. Beretta, M. Schonlein, V. Gambacorta, F. M. Aletti, M. G. Carraba, C. Bonini, F. Ciceri, I. Merelli, , R. Di Micco

This study shows therapy-induced senescence in AML upregulates antigen presentation and enhances T-cell anti-leukemic activity, suggesting senescence as a target for immunotherapy.

bioRxiv · Nov 17, 2022 · PreprintCancer Biology

Follicular helper T cell signature of replicative exhaustion, apoptosis and senescence in common variable immunodeficiency

G. Milardi, B. Di Lorenzo, J. Gerosa, F. Barzaghi, G. Di Matteo, M. Omrani, T. Jofra, I. Merelli, M. Barcella, F. Ferrua, F. P. Giuffrida, F. Dionisio, P. Rovere-Querini, S. Marktel, A. Assanelli, , C. Cancrini

The paper identifies a subset of CVID patients with Tfh cells showing replicative exhaustion, apoptosis, and senescence linked to DNA repair and telomere elongation defects.

bioRxiv · Jun 15, 2021Immunology

The lysine-rich intracellular loop and cell type-specific co-factors are required for IFITM3 antiviral immunity in hematopoietic stem cells

G. Unali, A. M. S. Giordano, I. Cuccovillo, M. Abou Alezz, L. Apolonia, I. Merelli, M. M. Malim, C. Petrillo, A. Kajaste-Rudnitski

This study identifies lysine residues in IFITM3 and cell type-specific co-factors as critical for its antiviral activity in hematopoietic stem cells, revealing a mechanism that can be modulated by Cyclosporine H.

bioRxiv · Apr 6, 2021 · PreprintMicrobiology