IRG1 controls host responses to restrict Mycobacterium tuberculosis infection
A. Machelart, I. Belhaouane, N. Deboosere, I. Poncin, J.-P. Saint-Andre, A.-M. Pauwels, O.-R. Song, S. Jouny, C. Rouanet, A. Poncet, S. Marion, W. Laine, J. Kluza, E. Muraille, R. Beyaert, , E. Hoffmann
This study shows that IRG1 controls host responses to restrict Mycobacterium tuberculosis infection by modulating immune cell function and limiting bacterial replication.
bioRxiv · May 4, 2022 · PreprintImmunology