Author

E. Hoffmann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Assay:metagenomics· 1

Frequent Co-Authors

A. Machelart· 2 shared N. Deboosere· 2 shared P. Brodin· 2 shared A. Berr· 1 shared A. Biela· 1 shared A. Danneels· 1 shared A. Poncet· 1 shared A. Vandeputte· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersImmunology

A. Machelart

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Target of rapamycin (TOR) regulates CURLY LEAF (CLF) translation in response to environmental stimuli

D. Yihan, E.-Z. Oubassou, E. Hoffmann, W. Zhang, V. V. Uslu, A. Berr

This study shows that TOR regulates CLF translation via an upstream open reading frame, affecting stress response and developmental gene induction.

bioRxiv · Jun 28, 2024 · PreprintPlant Biology

IRG1 controls host responses to restrict Mycobacterium tuberculosis infection

A. Machelart, I. Belhaouane, N. Deboosere, I. Poncin, J.-P. Saint-Andre, A.-M. Pauwels, O.-R. Song, S. Jouny, C. Rouanet, A. Poncet, S. Marion, W. Laine, J. Kluza, E. Muraille, R. Beyaert, , E. Hoffmann

This study shows that IRG1 controls host responses to restrict Mycobacterium tuberculosis infection by modulating immune cell function and limiting bacterial replication.

bioRxiv · May 4, 2022 · PreprintImmunology

Clofoctol inhibits SARS-CoV-2 replication and reduces lung pathology in mice

S. Belouzard, A. Machelart, V. Sencio, T. Vausselin, E. Hoffmann, N. Deboosere, Y. Rouille, L. Desmarets, K. Seron, A. Danneels, C. Robil, L. Belloy, C. Moreau, C. Piveteau, A. Biela, , J. Dubuisson

This paper identifies clofoctol as an antiviral against SARS-CoV-2, showing it inhibits viral replication and reduces lung pathology in mice.

bioRxiv · Jun 30, 2021 · PreprintMicrobiology