Inflammatory monocytes promote pyogranuloma formation to counteract Yersinia blockade of host defense
D. Sorobetea, R. Matsuda, S. T. Peterson, J. P. Grayczyk, I. Rao, E. Krespan, M. Lanza, C.-A. Assenmacher, D. P. Beiting, E. Radaelli, I. E. Brodsky
This study shows that Yersinia pseudotuberculosis induces pyogranulomas in the murine intestine by blocking phagocytosis, and that monocytes are essential for granuloma formation and immune control.
bioRxiv · Feb 6, 2022 · PreprintMicrobiology