Molecular mechanism of light-driven sodium pumping
K. Kovalev, R. Astashkin, I. Gushchin, P. Orekhov, D. Volkov, E. Zinovev, E. Marin, M. Rulev, A. Alekseev, A. Royant, P. Carpentier, S. Vaganova, C. Baeken, I. Sergeev, D. Zabelskii, , V. Gordeliy
The paper elucidates the molecular mechanism of Na+ pumping by KR2 rhodopsin using crystal structures and molecular dynamics, revealing a switching mechanism and structural similarities to channelrhodopsins.
bioRxiv · Jan 29, 2020Biophysics