Genome dilution by cell growth drives starvation-like proteome remodeling in mammalian and yeast cells
M. C. Lanz, S. Zhang, M. P. Swaffer, L. Hernandez Götz, F. McCarty, I. Ziv, D. F. Jarosz, J. E. Elias, J. M. Skotheim
The paper shows that increasing cell size leads to proteome remodeling similar to starvation, driven by genome dilution in mammalian and yeast cells.
bioRxiv · Oct 16, 2023Cell Biology