Author

Imke L. Lemmer

Helmholtz Munich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:metagenomics· 1

Frequent Co-Authors

Aleksander C. LazarskiiD· 1 shared Alexander BarteltiD· 1 shared Anahita Ofoghi· 1 shared Anna JungiD· 1 shared Batoul Bayer· 1 shared Chloe Y. ZhangiD· 1 shared Daniel Thomas Haas· 1 shared Deepesh PanwariD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Aleksander C. LazarskiORCID

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2 papers

Recent·Most cited

Activating the NFE2L1-ubiquitin-proteasome system by DDI2 protects from ferroptosis

Anahita Ofoghi, Stefan Kotschi, Imke L. Lemmer, Daniel Thomas Haas, Nienke Willemsen, Batoul Bayer, Anna Jung, Sophie Möller, Stefanie Haberecht-Müller, Elke Krüger, Natalie Krahmer, Alexander Bartelt

This study shows that DDI2 activates NFE2L1 to protect cells from ferroptosis by regulating the ubiquitin-proteasome system.

Cell Death and Differentiation · Oct 9, 2024Peer-reviewedMolecular Biology

Functional metagenomics reveals an alternative, broad-specificity pathway for metabolism of carbohydrates in human gut commensal bacteria

Seyed A. Nasseri, Aleksander C. Lazarski, Imke L. Lemmer, Chloe Y. Zhang, Eva Brencher, Hongming Chen, Lyann Sim, Deepesh Panwar, Leo Betschart, L.J. Worrall, Harry Brumer, Natalie C. J. Strynadka, Stephen G. Withers

The paper identifies a novel, broad-specificity glycosidase pathway in gut bacteria that operates via a non-Koshland mechanism, capable of hydrolyzing diverse substrates including thioglycosides and pharmaceuticals.

Nature · Jun 19, 2024Peer-reviewedBiochemistry