Author

Iris Bachmutsky

University of California, Los Angeles

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1 Organism:human· 1

Frequent Co-Authors

Adelae Durand· 1 shared Allison Foreman· 1 shared Anna‐Leigh BrowniD· 1 shared Apoorva L. MylavarapuiD· 1 shared Ariana P. GattiD· 1 shared Bence RácziD· 1 shared Daniel H. GeschwindiD· 1 shared Dario DattiloiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperNeuroscience

Adelae Durand

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3 papers

Recent·Most cited

TDP-43 dysfunction induces cryptic circular RNAs in ALS/FTD

Dario Dattilo, Flaminia Pellegrini, Simone Barattucci, Anna‐Leigh Brown, Jose Norberto S. Vargas, Ariana P. Gatt, Ryan D. Morrie, Georgiana Miller, Iris Bachmutsky, Zachary T. McEachin, Mingee Chung, Matthew J. Keuss, Eugeni M. Ryadnov, Matteo Zanovello, Puja R. Mehta, , Pietro Fratta

This study identifies TDP-43 dysfunction as a cause of cryptic circular RNA formation in ALS/FTD, showing their association with disease-relevant protein loss and potential as biomarkers.

bioRxiv · Sep 20, 2026 · PreprintNeuroscience

β2-Arrestin germline knockout does not attenuate opioid respiratory depression

Iris Bachmutsky, Xin Paul Wei, Adelae Durand, Kevin Yackle

This paper shows that β2-Arrestin germline knockout does not reduce opioid-induced respiratory depression in mice, challenging the biased agonist hypothesis.

eLife · May 18, 2021Peer-reviewedNeuroscience

Reduced prefrontal synaptic connectivity and disturbed oscillatory population dynamics in the CNTNAP2 model of autism

María T. Lázaro, Jiannis Taxidis, Tristan Shuman, Iris Bachmutsky, Taruna Ikrar, Rommel Andrew Santos, G. Mark Marcello, Apoorva L. Mylavarapu, Swasty Chandra, Allison Foreman, Rachna Goli, Duy Tran, Nikhil Sharma, Michelle Azhdam, Hongmei Dong, , Peyman Golshani

This study investigates the effects of CNTNAP2 loss-of-function mutations in mice, finding reduced synaptic connectivity and altered oscillatory dynamics in the prefrontal cortex associated with autism-like behaviors.

Cell Reports · May 1, 2019Peer-reviewedNeuroscience