Effects of SGLT2 Ablation or Inhibition on Corticosterone Secretion in High-Fat-Fed Mice: Exploring a Nexus with Cytokine Levels
Niki F. Brisnovali, Isabelle Franco, Amira Abdelgawwad, Hio Lam Phoebe Tsou, Thong Huy Cao, John E. McDonald, Antonio Riva, Guy A. Rutter, Elina Akalestou
This study investigates the effects of SGLT2 inhibition or deletion on corticosterone secretion and cytokine levels in high-fat-fed mice, revealing links between SGLT2 activity, immune modulation, and metabolic homeostasis.
Diabetologia · Jun 20, 2025Peer-reviewedCell Biology