Author

J. A. Fallas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

D. Baker· 2 shared G. Ueda· 2 shared H. Ruohola-Baker· 2 shared J. Mathieu· 2 shared S. Saini· 2 shared Y. T. Zhao· 2 shared A. C. Walls· 1 shared A. Etemadi· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

D. Baker

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Designed proteins assemble antibodies into modular nanocages

R. Divine, H. V. Dang, G. Ueda, J. A. Fallas, I. Vulovic, W. Sheffler, S. Saini, Y. T. Zhao, I. X. Raj, P. A. Morawski, M. F. Jennewein, L. J. Homad, Y.-H. Wan, M. R. Tooley, F. Seeger, , D. Baker

The paper designs modular nanocages that assemble antibodies into precise geometries, enhancing signaling and neutralization compared to free antibodies.

bioRxiv · Dec 1, 2020Biochemistry

F-domain valency determines outcome of signaling through the angiopoietin pathway

Y. T. Zhao, J. A. Fallas, S. Saini, G. Ueda, L. Somasundaram, Z. Zhou, I. Xavier, D. Ehnes, C. Xu, L. Carter, S. Wrenn, J. Mathieu, D. L. Sellers, D. Baker, H. Ruohola-Baker

The paper investigates how the valency of F-domain scaffolds affects signaling through the angiopoietin pathway, finding that higher valency mimics Ang1's pro-angiogenic effects while lower valency mimics Ang2's antagonistic effects.

bioRxiv · Sep 19, 2020Biochemistry