Author

L. Somasundaram

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

C. Xu· 1 shared D. Baker· 1 shared D. Ehnes· 1 shared D. L. Sellers· 1 shared D. Wang· 1 shared E. Troemel· 1 shared G. Ueda· 1 shared G. Xu· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

C. Xu

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2 papers

Recent·Most cited

BiochemistrybioRxivSep 19, 2020

F-domain valency determines outcome of signaling through the angiopoietin pathway

Y. T. Zhao, J. A. Fallas, S. Saini…·H. Ruohola-Baker

The paper investigates how the valency of F-domain scaffolds affects signaling through the angiopoietin pathway, finding that higher valency mimics Ang1's pro-angiogenic effects while lower valency mimics Ang2's antagonistic effects.

DOI 10.15252/embr.202153471

proteomicsexperimental assay

𝕏 PostBluesky

MicrobiologybioRxivJul 18, 2019

The C. elegans RIG-I homolog drh-1 mediates the Intracellular Pathogen Response upon viral infection

J. N. Sowa, H. Jiang, L. Somasundaram…·E. Troemel

This paper shows that drh-1 in C. elegans mediates the Intracellular Pathogen Response (IPR) to viral infection, acting as a pattern-recognition receptor independent of its role in RNAi.

DOI 10.1128/jvi.01173-19

C. elegansbulk RNA-seq

𝕏 PostBluesky