Author

J. Adjaye

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Organism:human· 4 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

L. Erichsen· 3 shared W. Wruck· 3 shared M. Bohndorf· 2 shared A. S. Reichert· 1 shared C. Berndt· 1 shared C. Thimm· 1 shared K. Schichel· 1 shared L. D. F. Klos· 1 shared

Activity by Year

2021-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersCell Biology

L. Erichsen

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

JNK signalling regulates self-renewal of proliferative urine-derived renal progenitor cells via inhibition of ferroptosis

L. Nguyen, M. Westerhoff, L. Thewes, W. Wruck, A. S. Reichert, C. Berndt, J. Adjaye

This study shows JNK signaling supports self-renewal of urine-derived renal progenitor cells by preventing ferroptosis, suggesting its role in kidney disease modeling.

bioRxiv · Aug 24, 2022 · PreprintCell Biology

Derivation of the immortalized cell line-UM51-PrePodo-hTERT and its responsiveness to Angiotensin II and activation of RAAS

L. Erichsen, L. D. F. Klos, C. Thimm, M. Bohndorf, K. Schichel, W. Wruck, J. Adjaye

The paper describes the derivation of an immortalized human podocyte cell line and demonstrates its responsiveness to Angiotensin II and RAS activation.

bioRxiv · May 23, 2022Cell Biology

Crosstalk between age accumulated DNA-damage and the SIRT1-AKT-GSK3b axis in urine derived renal progenitor cells

L. Erichsen, J. Adjaye

This study shows that aging in urine-derived renal progenitor cells is associated with reduced SIRT1 and its downstream targets AKT and GSK3β, increased DNA damage, and methylation of the SIRT1 promoter, linking these changes to stemness maintenance and aging hallmarks.

bioRxiv · May 7, 2022Cell Biology

Angiotensin II disrupts the cytoskeletal architecture of human urine-derived podocytes and results in activation of the renin-angiotensin system

L. Erichsen, M. Bohndorf, M. S. Rahman, W. Wruck, J. Adjaye

This study shows that angiotensin II disrupts podocyte cytoskeletal architecture and activates the renin-angiotensin system in urine-derived podocytes.

bioRxiv · Mar 18, 2021 · PreprintCell Biology