A. S. Reichert

This study identifies SLP2 as an auxiliary MICOS subunit that interacts with MIC13 to seed MIC60 assembly and promote crista junction formation.

The paper uses live-cell nanoscopy to study cristae dynamics under various bioenergetic conditions and finds that cristae remodeling is independent of mitochondrial membrane potential but affected by ADP/ATP exchange.

This study shows 4EBP1/2 promote cell survival under glucose starvation by repressing fatty acid synthesis and maintaining redox balance, supporting tumorigenicity in cancer cells.

This study shows JNK signaling supports self-renewal of urine-derived renal progenitor cells by preventing ferroptosis, suggesting its role in kidney disease modeling.

This study identifies OMA1's role in maintaining mitochondrial ultrastructure and bioenergetics through its interaction with the MICOS complex, showing its importance in cellular stress responses and apoptosis.

This study identifies SIRT4 as a centrosomal and microtubule-associated protein that delays mitotic progression and reduces cell proliferation.

The paper shows ammonia inhibits astrocyte energy metabolism via GDH2-dependent mechanisms, disrupting mitochondrial respiration and the TCA cycle under hyperammonemia.

The paper uses live-cell imaging to show mitochondrial cristae undergo continuous fusion and fission, dependent on MIC13, with dynamics similar to crista junctions.