Deletion of CD226 in Foxp3+ T cells Reduces Diabetes Incidence in Non-Obese Diabetic Mice by Improving Regulatory T Cell Stability and Function
P. Thirawatananond, M. Brown, L. Sachs, J. Arnoletti, W.-I. Yeh, A. L. Posgai, M. Shapiro, Y.-G. Chen, T. Brusko
This study shows that deleting CD226 in regulatory T cells reduces diabetes in NOD mice by enhancing Treg stability and function.
bioRxiv · Jun 2, 2022 · PreprintImmunology