Author

J. B. Klauda

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:electrophysiology· 1 Approach:experimental assay· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

M. Ghorbani· 3 shared B. R. Brooks· 2 shared P. B. Tiwari· 1 shared T. I. I. Brelidze· 1 shared X. Chen· 1 shared Z.-J. Wang· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 11 mutual co-author links

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3 shared papersBiophysics

M. Ghorbani

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3 papers

Recent·Most cited

Chlorpromazine inhibits EAG1 channels by altering the coupling between the PAS, CNBH and pore domains

M. Ghorbani, Z.-J. Wang, X. Chen, P. B. Tiwari, J. B. Klauda, T. I. I. Brelidze

This study shows chlorpromazine inhibits EAG1 channels by disrupting PAS-CNBH domain coupling, without affecting VSD movement.

bioRxiv · Feb 23, 2024 · PreprintBiophysics

Exploring dynamics and network analysis of spike glycoprotein of SARS-COV-2

M. Ghorbani, B. R. Brooks, J. B. Klauda

This study uses MD simulations and network analysis to investigate the dynamics and shielding role of glycans in the SARS-CoV-2 spike protein, identifying key glycans and microdomains that hinder antibody access.

bioRxiv · Sep 28, 2020Biophysics

Critical Sequence Hot-spots for Binding of nCOV-2019 to ACE2 as Evaluated by Molecular Simulations

M. Ghorbani, B. R. Brooks, J. B. Klauda

This study identifies critical sequence hotspots for nCOV-2019 RBD binding to ACE2 using molecular simulations, highlighting implications for transmission, vaccine design, and drug development.

bioRxiv · Jun 27, 2020Biophysics