Cancer BiologybioRxivPreprint
Pancreatic cancer ductal cell of origin drives CD73-dependent generation of immunosuppressive adenosine
K. Singh, E. Y. Faraoni, Y. Dai…·J. Bailey Lundberg
This study identifies CD73 as a key driver of immunosuppression in pancreatic ductal adenocarcinoma, showing its role in adenosine generation and tumor progression.