Author

J. Borison

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Cancer Biology· 1

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

A. J. Ritchie· 1 shared A. T. Mayer· 1 shared E. A. Collisson· 1 shared H. Jiang· 1 shared L. Lupin-Jimenez· 1 shared M. F. Krummel· 1 shared T. Courau· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. J. Ritchie

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1 paper

Recent·Most cited

Activating Immune Recognition in Pancreatic Ductal Adenocarcinoma Using Autophagy Inhibition, MEK blockade and CD40 Agonism

H. Jiang, T. Courau, L. Lupin-Jimenez, J. Borison, A. J. Ritchie, A. T. Mayer, M. F. Krummel, E. A. Collisson

This study shows that combining MEK inhibition, autophagy inhibition, and CD40 agonism activates the Type I Interferon/STING pathway in PDA tumors, reprograms TAMs, and enhances anti-tumor immunity in a mouse model.

bioRxiv · Nov 5, 2020 · PreprintCancer Biology