Author

J. Bourseguin

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Cell Biology· 1

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

E. Talbot· 1 shared L. Hardy· 1 shared S. V. Khoronenkova· 1 shared W. Cheng· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperCell Biology

E. Talbot

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1 paper

Recent·Most cited

Cell BiologybioRxivJun 2, 2021

Persistent DNA damage promotes microglial dysfunction in Ataxia-telangiectasia

J. Bourseguin, W. Cheng, E. Talbot…·S. V. Khoronenkova

This study shows that DNA damage in Ataxia-telangiectasia leads to microglial dysfunction via the RELB/p52 pathway, causing excessive neurite phagocytosis and contributing to neurodegeneration.

DOI 10.1093/nar/gkac104

humanproteomics