Interactions of the Protein Tyrosine Phosphatase PTPN3 with Viral and Cellular Partners through its PDZ Domain: Insights into Structural Determinants and Phosphatase Activity
M. Genera, B. Colcombet-Cazenave, A. Croitoru, B. Raynal, A. Mechaly, J. Caillet, A. Haouz, N. Wolff, C. Caillet-Saguy
This study investigates the interactions of PTPN3's PDZ domain with viral and cellular PBMs, revealing structural determinants and the inhibitory role of the PDZ domain on phosphatase activity.
bioRxiv · Mar 23, 2023 · PreprintBiophysics