Solid state NMR reveals a parallel in register architecture for an infectious recombinant prion
M. Martin-Pastor, Y. B. Codeseira, G. Spagnolli, H. Erana, L. C. Fernandez, D. Martin, S. Bravo, N. Lopez-Lorenzo, A. Iglesias, R. Lopez-Moreno, R. Sabate, S. Veiga, H. Rezaei, E. Biasini, V. M. Sanchez-Pedregal, , J. R. Requena
The paper uses solid state NMR to analyze the structure of infectious recombinant prion, finding support for the parallel in register beta stack model over the 4-rung beta-solenoid model.
bioRxiv · Jul 20, 2021 · PreprintBiochemistry