Prednisolone rescues Duchenne Muscular Dystrophy phenotypes in human pluripotent stem cells-derived skeletal muscle in vitro
Z. Al Tanoury, J. F. Zimmermann, J. Rao, D. Siero, H. McNamara, T. Cherrier, A. Hick, F. Bousson, C. Fugier, F. Marchiano, B. Habermann, J. Chal, A. P. Nesmith, S. Gapon, E. Wagner, , O. Pourquie
This study shows prednisolone rescues DMD phenotypes in iPSC-derived muscle cells, suggesting direct myofiber effects rather than just anti-inflammatory benefits.
bioRxiv · Oct 29, 2020Cell Biology