A conserved activity for cohesin in bridging DNA molecules
P. Gutierrez-Escribano, M. Newton, A. Llauro, J. Huber, L. Tanasie, J. Davy, I. Aly, R. Aramayo, A. Montoya, H. Kramer, J. Stigler, D. Rueda, L. Aragon
This study identifies a conserved DNA bridging activity of cohesin complexes across species, revealing two bridge types with distinct force resistance and functional implications for cohesion and chromosome architecture.
bioRxiv · Sep 5, 2019 · PreprintBiochemistry